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PICO is an acronym used to identify the key components of a clinical research question.Use PICO to break down your question into smaller parts and identify keywords in order to find relevant literature to help formulate an answer.
In recent years, T for time frame has been added. The examples below do not include T.
P |
I |
C |
O |
Patient/Problem/Population |
Intervention/Indicator |
Compare/Control(where applicable) |
Outcome |
Who are the patients you want to study? Think of age, sex, geography when trying to determine who it is you are interested in looking at. | What is the intervention you are interested in? (medical, surgical, preventative?) | Is there an alternative strategy to consider? | What are the patient-relevant consequences of the intervention? |
Example 1: Patients with chronic pain | Acupuncture | Medication |
Pain management |
Example 2: Seniors/elderly | Aspirin | No aspirin | Reduce risk of heart attacks |
Example 3: Children with autism spectrum disorder | Cognitive behaviour therapy | N/A | Reduce anxiety |
Question Example 1: In patients with chronic pain does acupuncture manage pain better than medication?
Question Example 2: In seniors does Aspirin reduce the risk of heart attacks?
Question Example 3: Does cognitive behaviour therapy reduce anxiety in children with autism spectrum disorder?